Clear-Cut and Precise HbA1c separation accessible to all laboratories

Test presentation

Following the introduction of CAPILLARYS Hb A1c in 2011, to allow small to medium size laboratories to benefit from this next generation separation method, Sebia adapted this high resolution technology for the MINICAP FLEX-PIERCING instrument.

From whole blood sampling in primary capped tubes to the final result, the MINICAP FLEX-PIERCING instrument performs all sequences automatically.

The clear-cut and precise separation of the different hemoglobin fractions allows accurate HbA1c measurement with no altered results in the presence of frequent interferences (labile A1c, carbamylated Hb, Hb F, Hb S, Hb C, Hb D and Hb E) as well as the incidental detection of the common hemoglobin disorders (sickle  cell, beta-thalassemia…). Using the IFCC reference method calculation formula HbA1c/(HbA1c+HbA0), developed for the worldwide assay standardization, the Sebia methodology ensures accurate and reliable results.  



Test principle

The MINICAP Hb A1c assay is based on the principle of capillary electrophoresis in free solution. Hemoglobin fractions are separated in silica capillaries, by their electrophoretic mobility and electroosmotic flow at a high voltage in an alkaline buffer. During migration, hemoglobin fractions are directly detected at an absorbance of 415 nm.




  • Throughput: 8 tests/h
  • Between-run CVs: <2%
  • Full traceability and positive sample ID for blood samples and reagents
  • Cap piercing and mixing from primary tubes
  • Rapid validation through color-coded profiles using the mosaic screen

Kit description

MINICAP Hb A1c (PN 2215) kit content:

  • Buffer
  • Hemolyzing solution
  • Wash solution
  • Dilution cups
  • Filters
  • Bins for used cups


Related products and accessories not provided in the kit:

  • Multi-system Hb A1c capillary controls (2 levels) (PN 4768)
  • Hb A1c capillary calibrators (2 levels) (PN 4755)
  • Tubes and caps for controls (PN 9202 / PN 9205)
  • Automatic low volume labels (PN 9208)
  • Manual low volume labels (PN 9209)
  • CAPIprotect (2 x 5L) (PN 2061)

Compatible Instruments


NOTE: Contact your Sebia representative to verify the product availability in your country.