Diagnosis criteria of multiple sclerosis (MS) have evolved over time incorporating the imaging findings. The two major changes in the 2017 revision are :
- the early diagnosis of multiple sclerosis can be made in patients with clinically isolated syndrome (CIS) , demonstration of dissemination of space on Magnetic Resonance Imaging (MRI) , and the presence of CSF-specific oligoclonal bands, without the need for demonstration of dissemination of time on MRI
- symptomatic and/or asymptomatic MRI lesions, except those in the optic nerve, can be considered in the determination of dissemination in space or time.
The presence of cerebrospinal-fluid-specific oligoclonal bands allows the diagnosis of multiple sclerosis in selected patients.
CNS Local IgG synthesis detection by isoelectrofocusing
The gold standard assay to objectively detect CNS local IgG synthesis in multiple sclerosis.
CNS Local IgG synthesis detection by isoelectrofocusing
The gold standard assay to objectively detect CNS local IgG synthesis in multiple sclerosis.
CNS Local IgG synthesis detection by isoelectrofocusing
The gold standard assay to objectively detect CNS local IgG synthesis in multiple sclerosis.
CNS Local IgG synthesis detection by isoelectrofocusing
The gold standard assay to objectively detect CNS local IgG synthesis in multiple sclerosis.
CNS Local IgG synthesis detection by isoelectrofocusing
The gold standard assay to objectively detect CNS local IgG synthesis in multiple sclerosis.
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