About
The Sebia systems use the principle of capillary electrophoresis (CE) in free solution.
Charged molecules are separated by their electrophoretic mobility at a specific pH in an alkaline buffer.
Separation occurs according to the electrolyte pH and electroosmotic flow. CE has a steady flow, compared to the pumped parabolic flow of the High-Performance Liquid Chromatography technique (HPLC). The steady flow results in narrower peaks and better resolution.
The Sebia capillary electrophoresis instruments are equipped with several parallel capillaries enabling multiple simultaneous analyses and scalable throughput:
Sebia’s Expertise
8,000 SEBIA CE instruments running everyday around the world.
Clinical & Analytical performances
- Dynamic separation and high resolution
- Changes to complex and multimolecular profiles
- Quantification of small molecules/post-translational modifications
- Powerful separation technology
- Indisputable quality
- Recognized capillary performance (EEQ, Evaluations etc.)
Operational efficiency
- Turn your routine gel tests into a fully automated technique (SPE, UPE, IF, Hemoglobin)
- Fast and accurate measurements for diagnosis and monitoring
- Short analysis time and fully automated
- Minimum waste production
Featured resources on Capillary Electrophoresis
See all resourcesEurA1c trial
The EurA1c trial, organized yearly, investigates the performance of HbA1c assays across countries and manufacturers.
The simple principles of innovative Capillary electrophoresis testing
Understand in 2 minutes how capillary electrophoresis works, and why it gives such high and clear resolution in lab testing.
Further evaluation of the world health organization international reference reagent for Haemoglobin A2 measurement
This article assesses the performances of the different manufacturers and technologies (HPLC and CE) for Hb A2 measurement using both International Reference Reagent for HbA2 (WHO IRR 89/666) and analysis of three whole blood specimens over a range of HbA2, distributed to 56 laboratories located in 14 different countries.
Precision of CAPILLARYS 2 for the Detection of Hemoglobin Variants Based on Their Migration Positions
In this report, we evaluated the use of the capillary electrophoresis (CE) migration position in the CAPILLARYS 2 CE instrument.
The impact of red blood cell lifespan on HbA1c measurement
This article reminds the reader of the importance of detecting the Hb variants when measuring HbA1c for the labs and clinicians to better interpret the results and to ensure optimal management of the diabetic patient.
Effects of hemoglobin C, D, E and S traits on measurements of hemoglobin A1c by twelve methods
Hemoglobin C, D Punjab, E or S trait can interfere with hemoglobin A1c (HbA1c) results depending on the method of analysis used. Therefore, it is important to know the limitations of the method used for HbA1c determination.
Carbohydrate-deficient transferring testing: a truly traceable and specific biomarker for chronic alcohol misuse
Article from Jean Deenmamode, IFCC CDT working group chair in CLI magazine.
Interview with M. Jean Deenmamode, CDT IFCC Working Group Chair
Interview between Sebia and M. Jean Deenmamode, CDT IFCC Working Group Chair
Standardisation of the CDT measurement on CAPILLARYS 3 TERA
IFCC Standardisation of the Sebia CDT measurement on CAPILLARYS 3 TERA.
International standardization of CDT measurement
IFCC CDT-Working Group standardized the CDT measurement.
Multiple Myeloma clinical cases for diagnosis and monitoring according to latest IMWG recommendations
Educational Webinar with Prof. Alessandro Gozzetti, MD, PhD
Performance of Immunotyping vs. Immunofixation for the Detection of Monoclonal Gammopathies
Educational Webinar with Katie Thoren, PhD, Memorial Sloan Kettering Cancer Center
Hemoglobinopathy Testing: What are the Key Points a Lab Should Consider?
Educational Webinar Dr. Cornelia L. Harteveld from Leiden University Medical Center
Performance of HbA1c Assays in relation to clinical requirements for its use in diabetes
Educational Webinar with Dr. Cas WEYKAMP
CAPILLARYS 3 DBS – Introductory video
The perfect match for screening hemoglobin disorders in newborns
Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies – MDPI – 2019
This special Issue related to newborn screening for Sickle Cell disease and other hemoglobinopathies tried to cover the most widely faced challenges in the field of newborn screening for SCD.
Moving from IF to Immunotyping Testing to Increase Productivity and Reduce Errors in M-protein Identification
Learn how a Sebia customer utilized our Workflow Service offering and CAPILLARYS 3 instruments to achieved higher throughput and improved workflow.
Early detection of Multiple Myeloma: The importance of serum protein electrophoresis
Educational Webinar with Dr. Julien GUILLEMAUD
Clinical and Operational Aspects of Measuring Hemoglobin A1c by Capillary Electrophoresis
Educational Webinar with David G. Grenache, PhD, D(ABCC)
Chief Scientific Officer, TriCore Reference Laboratories
Moving from Immunofixation to Immunotyping Improves Standard of Care by Hand-on and Turnaround Time
Learn how a Sebia customer gained both clinically and operationally with a simplified IT workflow.
Challenges in Implementing Capillary Electrophoresis for Immunotyping
Educational Webinar with Dr. Jack Maggiore from Loyola University Medical Center in Chicago, IL
Hemoglobinopathy Investigation – The Case for Capillary Electrophoresis
Educational Webinar with Jason EYRE
Discover the main applications related to the CDT marker
CDT is a sensitive and specific marker of chronic alcohol abuse, used in several contexts and notably including forensic settings, industries, clinical applications.
How External Quality Assessment supports quality improvement in laboratory hemoglobinopathy diagnosis
Educational Webinar with Dr. Barbara De la Salle
To see or not A1c? HbA1c utilization in light of recent lab guidelines
Educational Webinar with Dr. Matthew C. Wagner
Upcoming events
See all events
MINICAP FLEX-PIERCING
The compact and affordable automation of Capillary Electrophoresis.
CAPILLARYS 3 TERA MC
The power of up to 36 capillaries in one automated high volume workcell.
CAPILLARYS 3 DBS
The high throughput solution for newborn hemoglobin disorders screening.
Serum Protein by Capillary Electrophoresis
High throughput Serum Protein Electrophoresis with high resolution results.
Urine Protein by Capillary Electrophoresis
High throughput Urine Protein Electrophoresis, with high resolution results.
Serum and Urine Immunotyping
Fully automated monoclonal proteins identification by Capillarys electrophoresis.
Hemoglobin disorders screening
The high-resolution method for hemoglobin disorders screening.
Carbohydrate Deficient Transferrin (CDT)
The most reliable chronic alcohol abuse marker.
Newborn hemoglobin disorders screening
The perfect match for screening hemoglobin disorders in newborns.
This section contains information intended for wide distribution and may therefore contain product details or information that is not available or valid in your country.
Please contact your local Sebia representative. Information intended for healthcare professionals.
Carefully read the instructions in the reagent package inserts and instrument manuals.