Serum Protein by Capillary Electrophoresis
High throughput Serum Protein Electrophoresis with high resolution results.
About Serum Protein by Capillary Electrophoresis
Serum Protein Electrophoresis is a well-established technique routinely used in clinical laboratories to detect protein abnormalities. It is used to screen and monitor disease states such as monoclonal gammopathies (Multiple Myeloma, MGUS, Waldenström disease) and indentify inflammatory disease patterns.
Key benefits
Fully automated and high throughput testing
for fast serum protein separation with high resolution.
Direct visualisation of Serum Protein profile
for quick screening and identification of abnormal patterns.
Separation into major protein fractions
CAPI 3 PROTEIN(E) 6 kit enables the separation into six major fractions: Albumin, Alpha-1, Alpha-2, Beta-1, Beta-2, Gamma.
Ability to quantify abnormal peaks in two modes
Valley to valley or Baseline to top.
Main characteristics
Serum Proteins are separated in silica capillaries by their electrophoretic mobility and the electroosmotic flow at high voltage in an alkaline buffer. Proteins are directly detected during migration by UV absorbance at 200 nm and quantified by the peak quantification tool.
Serum
- Full traceability and positive sample ID from primary tube samples
- Full traceability and reagents management through RFID tags
- Color-coded backlit reagent containers
- Rapid validation via 96 profile mosaic display
Sensitivity
- Monoclonal protein can be detected at a concentration as low as 19 mg/dL.
- According to the mobility of the monoclonal component and polyclonal background, the sensitivity may vary.
Large autonomy
- Samples up to 528 tubes (with tube loader)
- > 2.5 hours protein testing
Throughput (tests/hour)*
PROTEIN(E) 6
CAPILLARYS 3 OCTA 79
CAPILLARYS 3 TERA 99
CAPILLARYS 3 TERA MC3 243
MINICAP FLEX-PIERCING 20
Throughput (tests/hour)*
IMMUNOTYPING
CAPILLARYS 3 OCTA 9
CAPILLARYS 3 TERA 11
CAPILLARYS 3 TERA MC3 27
MINICAP FLEX-PIERCING 1.7
* Using Software version 9.30
- CAPI 3 PROTEIN(E) 6 – P/N: 2503
- MINICAP PROTEIN(E) 6 – P/N: 2203
Featured instruments for Serum Protein by Capillary Electrophoresis
See all instrumentsCAPILLARYS 3 TERA MC
The power of up to 36 capillaries in one automated high volume workcell.
MINICAP FLEX-PIERCING
The compact and affordable automation of Capillary Electrophoresis.
Related resources
See all resourcesPerformance of Immunotyping vs. Immunofixation for the Detection of Monoclonal Gammopathies
Educational Webinar with Katie Thoren, PhD, Memorial Sloan Kettering Cancer Center
Moving from IF to Immunotyping Testing to Increase Productivity and Reduce Errors in M-protein Identification
Learn how a Sebia customer utilized our Workflow Service offering and CAPILLARYS 3 instruments to achieved higher throughput and improved workflow.
Early detection of Multiple Myeloma: The importance of serum protein electrophoresis
Educational Webinar with Dr. Julien GUILLEMAUD
Moving from Immunofixation to Immunotyping Improves Standard of Care by Hand-on and Turnaround Time
Learn how a Sebia customer gained both clinically and operationally with a simplified IT workflow.
Challenges in Implementing Capillary Electrophoresis for Immunotyping
Educational Webinar with Dr. Jack Maggiore from Loyola University Medical Center in Chicago, IL
Scientific publications
See all publications
Interested in Serum Protein by Capillary Electrophoresis?
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Please contact your local Sebia representative. Information intended for healthcare professionals.
Carefully read the instructions in the reagent package inserts and instrument manuals.