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vWF multimer analysis is labor intensive, non standardized and limited to specialized laboratories.

This article performed in two European centers, compared existing in-house multimer assays to Hydragel VW multimer assay in individuals with and without von Willebrand Disease.

As Hydragel VW multimer densitometry improved the diagnosis of VWD, the authors suggest its use as an initial screen of vWF multimers in a VWD diagnostic algorithm in conjunction with traditional multimer analysis.

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