About
Sebia’s gel technology is based on the principle of separating of molecules in an agarose medium.
Three types of separation occur according to:
- The charge of the proteins, in a specific pH buffer
- The isoelectric point, in a specific pH gradient
- The molecular weight of the proteins, in an SDS-agarose gel
Sebia’s Expertise
With more than 50 years of experience in Gel Electrophoresis and more than 60 references, Sebia continues to develop and design the largest range of assays with the highest quality of standards.
The gel menu covers multiple pathologies including oncology (Multiple Myeloma), metabolic disorders such Hemoglobinopathies and rare pathologies in order to screen and monitor patients.
The multifunctional HYDRASYS 2 SCAN FOCUSING analyzer allows simultaneous sample analyses on one gel. Coupled with the ASSIST sample application, migration, washing, staining and scanning are performed on-board automatically in order to quantify the protein fractions.
Sebia’s gel solutions gives you confidence when reporting your patients’ results with best-in-class gel electrophoresis assays.
Featured resources on Gel Electrophoresis
See all resourcesHYDRASHIFT avoids monoclonal antibody interference on IMMUNOFIXATION
The HYDRASHIFT portfolio include IVD test to mitigate interferences seen in immunofixation result for patient treated with daratumumab.
Pitfalls and ceveats of A1AT diagnosis
Pitfalls and caveats in α1-antitrypsin deficiency testing: a guide for clinicians.
2005 Multiple Sclerosis Consensus Criteria
2005 Multiple sclerosis consensus criteria includes CSF IgG oligoclonal bands.
2017 Mc Donald Criteria for multiple sclerosis diagnosis
2017 Mc Donald Criteria for multiple sclerosis diagnosis includes CSF IgG oligoclonal bands.
Evaluation of Sebia’s isoelectrofocusing kit for A1AT
Evaluation of Sebia’s isoelectrofocusing kit for A1AT with HYDRASYS.
Experience and recommendations of a Major Cancer Center to use HYDRASHIFT daratumumab
Immunotherapies for Multiple Myeloma, like the monoclonal antibody daratumumab, can create false positive IgG Kappa bands on Immunofixation gels. This paper describes best practice guidelines for using the Hydrashift assay to remove daratumumab interference from Immunofixation gels.
Multiple Myeloma clinical cases for diagnosis and monitoring according to latest IMWG recommendations
Educational Webinar with Prof. Alessandro Gozzetti, MD, PhD
Performance of Immunotyping vs. Immunofixation for the Detection of Monoclonal Gammopathies
Educational Webinar with Katie Thoren, PhD, Memorial Sloan Kettering Cancer Center
Moving from IF to Immunotyping Testing to Increase Productivity and Reduce Errors in M-protein Identification
Learn how a Sebia customer utilized our Workflow Service offering and CAPILLARYS 3 instruments to achieved higher throughput and improved workflow.
Early detection of Multiple Myeloma: The importance of serum protein electrophoresis
Educational Webinar with Dr. Julien GUILLEMAUD
Moving from Immunofixation to Immunotyping Improves Standard of Care by Hand-on and Turnaround Time
Learn how a Sebia customer gained both clinically and operationally with a simplified IT workflow.
Upcoming events
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HYDRASYS 2 SCAN FOCUSING
Large menu with high quality results on gel electrophoresis.
CNS Local IgG synthesis detection by isoelectrofocusing
The gold standard assay to detect CNS local IgG synthesis in multiple sclerosis.
Alpha 1-Antitrypsin (A1AT) Phenotype Testing
The gold standard assay for the alpha 1-antitrypsin (A1AT) phenotype testing.
Urine Protein by Agarose Gel Electrophoresis
Proteinuria screening for renal disease.
Serum and Urine Immunofixation
Identification of monoclonal proteins by agarose gel electrophoresis.
Hemoglobin disorders screening
The high-resolution method for hemoglobin disorders screening.
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Please contact your local Sebia representative. Information intended for healthcare professionals.
Carefully read the instructions in the reagent package inserts and instrument manuals.