Newborn hemoglobin disorders
screening
The perfect match for screening hemoglobin disorders in newborns.
About Newborn Hemoglobin disorders screening
Every day more than one hundred thousand newborns are screened worldwide for metabolic and endocrine disorders.
Early screening has proven to be effective in improving the lives of babies by providing appropriate treatment and follow-up.
Key benefits
Ease of use
All the steps are managed automatically by the instrument; it is easy to operate and requires few maintenance procedures.
Automatic result interpretation
Samples are automatically identified as normal or abnormal by the software, allowing laboratories to quickly detect and identify pathological results.
Excellent resolution
Sebia’s high resolution capillary electrophoresis separation provides the display of a clear profile, enabling easy identification of abnormal hemoglobin variants (S, C, D and E…) as well as abnormalities arising from thalassemia (Bart’s).
Early detection
Early detection of hemoglobin disorders allows appropriate treatment and follow up, improving the infant’s life while reassuring parents.
Main characteristics
The CAPI 3 NEONAT Hb kit is intended as a qualitative screen for the detection of normal hemoglobins (F and A) and abnormal hemoglobins (S, C, E, D and Bart’s) in blood from human new-born collected on filter paper. This analysis is performed by capillary electrophoresis with the CAPILLARYS 3 DBS instrument.
Dried neonatal blood spots – Samples are punched (at 3.2 mm size), eluted in distilled water and analysed directly on the CAPILLARYS 3 DBS instrument.
Throughput (tests/hour)
CAPI 3 NEONAT Hb
CAPILLARYS 3 DBS 70
Dedicated reagent kit, Hemolysing solution and Hb AF control.
Reagents
- CAPI 3 NEONAT Hb – P/N: 2506
- CAPI 3 NEONAT Hemolysing solution – P/N: 2563
Controls
- CAPI 3 NEONAT Hb AF Control – P/N: 4757
- Hb AFSC Control* – P/N: 4792
* (optional pathological control)
Consumables
- CAPILLARYS 3 DBS Microplates – P/N: 2578
(10 units – 96 well barcoded microplates) - CAPILLARYS 3 CAPICLEAN – P/N: 2060
- CAPILLARYS 3 WASH SOLUTION – P/N: 2062
- CAPI 3 REAGENT CUPS (24 x 14) – P/N: 2582
Featured instruments for Newborn hemoglobin disorders screening
See all instrumentsCAPILLARYS 3 DBS
The high throughput solution for screening newborn hemoglobin disorders.
Related resources
See all resourcesCAPILLARYS 3 DBS – Introductory video
The perfect match for screening hemoglobin disorders in newborns
Scientific publications
See all publicationsNewborn Screening for Sickle Cell Disease and other Haemoglobinopathies – MDPI – 2019
This special Issue related to newborn screening for Sickle Cell disease and other hemoglobinopathies tried to cover the most widely faced challenges in the field of newborn screening for SCD.
Interested in Newborn hemoglobin disorders screening?
This section contains information intended for wide distribution and may therefore contain product details or information that is not available or valid in your country.
Please contact your local Sebia representative. Information intended for healthcare professionals.
Carefully read the instructions in the reagent package inserts and instrument manuals.