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Urine Protein by Capillary Electrophoresis

High throughput Urine Protein Electrophoresis, with high resolution results.

About Urine Protein by Capillary Electrophoresis

Urine Protein Electrophoresis is a well-established technique routinely used in clinical laboratories to detect and estimate the concentration of monoclonal components as Bence Jones proteins (Monoclonal Free Light Chains) or other proteinuria disorders.

Key benefits

Fully automated testing

for qualitative analysis with fast separation and good resolution with dedicated reagent and program on CAPILLARYS.

Direct visualisation of urine protein profile

for quick screening and identification of abnormal urinary pattern.

Separation into major protein fraction

CAPI 3 PROTEIN(E) 6 kit enables the separation into five major zones: Albumin, Alpha-1, Alpha-2, Beta, Gamma.

Ability to quantify abnormal peaks in two modes

Valley to valley or Baseline to top.

Main characteristics

Test Principle

Urine Proteins are separated in silica capillaries by their electrophoretic mobility and the electroosmotic flow at high voltage in an alkaline buffer. Proteins are directly detected during migration by UV absorbance and quantified by a peak.

Sample Type

Urine

Performances
  • Full traceability and positive sample ID for primary tube samples
  • Full traceability and reagents management through RFID tags
  • Color-coded backlit reagent containers
  • Rapid validation via 48 to 96 profile mosaic display

 

Sensitivity

Limit of detection with CAPI 3 URINE:

  • Protein abnormality is approximately 9 mg/L
  • Bence Jones protein is approximately 20 mg/L

 

Large autonomy

  • Samples up to 528 tubes (with tube loader)
  • >2.5 hours protein testing
Throughput

    Throughput (tests/hour)*

PROTEIN(E) 6

CAPILLARYS 3 OCTA                        70

CAPILLARYS 3 TERA                          97

CAPILLARYS 3 TERA MC3                238

 

    Throughput (tests/hour)*

IMMUNOTYPING

CAPILLARYS 3 OCTA                          9

CAPILLARYS 3 TERA                            11

CAPILLARYS 3 TERA MC3                  27

 

* Using Software version 9.30

Product details
  • CAPILLARYS / MINICAP URINE – P/N: 2013
  • CAPI 3 URINE – P/N: 2513

Featured instruments for Urine Protein by Capillary Electrophoresis

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CAPILLARYS 3 TERA MC

The power of up to 36 capillaries in one automated high volume workcell.

Related resources

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Performance of Immunotyping vs. Immunofixation for the Detection of Monoclonal Gammopathies

Webinar
Sep. 08, 2021

Educational Webinar with Katie Thoren, PhD, Memorial Sloan Kettering Cancer Center

Moving from IF to Immunotyping Testing to Increase Productivity and Reduce Errors in M-protein Identification

Whitepaper
Mar. 23, 2022

Learn how a Sebia customer utilized our Workflow Service offering and CAPILLARYS 3 instruments to achieved higher throughput and improved workflow.

Scientific publications

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Learn more about our unique technologies

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Please contact your local Sebia representative. Information intended for healthcare professionals.
Carefully read the instructions in the reagent package inserts and instrument manuals.