Connective tissue diseases (CTD) are Systemic Autoimmune Rheumatic Diseases (SARDs), a group of disorders characterized by inflammation and autoimmune reactions that affect multiple organ systems. These diseases involve the immune system attacking the body’s tissues, leading to widespread inflammation and damage. The most common SARDs are:
The diagnosis of CTD uses IFA (Immunofluorescence Assays) products and specific confirmatory tests. The gold standard of ANA determination (serological markers of CTD) is IFA, using human epithelial tumor cells (HEp-2), a stabilized cell line of human larynx carcinoma, known for its high sensitivity and specificity. In the context of CTD diagnosis is critical to identify the antibodies’ specificity. The Alegria monotest strip is a reliable solution offering a wide range of confirmatory tests, helping to save time and reduce reagent waste.
Sebia offers a reliable diagnostic path from the screening phase to the confirmation, by offering a combined workflow of ANA evaluation, and detection of the related antigens. This is done by using Sebia’s IFA test systems, the Alegria Monotest random access solution, and completed by the ELISA tests for high throughput tasks.
Sebia’s HEp-2 cells quality at a glance in a complete atlas of images.
A comprehensive overview of Sebia’s solutions for ANA screening for Connective tissue disease diagnosis.
The flexibility of Alegria monotest solution helps the correct stratification of the SLE patient population.
Obtain your patients results with high flexibility reliability and efficiency with Alegria 2.
The Alegria 2 provides the possibility of giving results to clinicians within a timeframe fitting clinical needs and helps to optimize the patient’s care pathway.
Small footprint – Big impact.
Perfect discrimination between Connective Tissue Diseases.
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